Cliu BioAnimation Studio is founded on the idea that basic biology should be engaging and accessible to everyone.

Watch the video to see this philosophy in action!

Part of my work focuses on bringing the wonder and awe of basic biomedical research and the discovery process to a wider audience.

The other part of my work involves working with clients directly to create animations and illustrations tailored to their particular need and budget.

I work across the entire video production pipeline, from scripting and storyboarding thru production and integration into the end platform. Visit the “Let’s Work Together” section at the end of this page to start your project with me!

I am constantly exploring and experimenting with more engaging ways of presenting biomedical topics visually.

This page displays some samples of my work, and is updated frequently!

K-Pop Demon Hunters ~ Immune Edition

K-Pop Demon Hunters ~ Immune Interpretation!

The Demons become pathogens ~ viruses and bacteria that can cause pandemic level harm to the human population, think the COVID-19 coronavirus, Influenza virus, and the Yersinia pestis bacteria.

Celine becomes a CD4 T cell ~ CD4 T cells license B cells and CD8 T cells to fight the infections! Without CD4 T cells, B cells and CD8 T cells would not be able to effectively fight the pathogens they were born to fight!

Bobby becomes a Macrophage ~ Macrophages are always functioning in the background, from everyday patrolling of the body, to producing cytokines to cheer immune cells on, to healing damaged tissues after an immune battle.

Mira becomes a Natural Killer Cell ~ Natural Killer cells are super fast and efficient. They kill cells in the body that are stressed or damaged. Lots of times, cell stress and damage can come from early infections, so Natural Killer cells act early to prevent possibly infected cells from becoming virus or bacteria factories!

Zoey becomes a B cell ~ since her throwing knives act so much like antibodies! Activated B cells, also called Plasma B cells, shoot out antibodies that are designed to target the surface proteins on viruses and bacteria. These antibodies bind to viral and bacterial surface proteins to block them from contacting surface proteins on our healthy cells, so preventing viruses and bacterias from latching onto and entering into our cells.

Rumi becomes a CD8 T cell ~ CD8 T cells are specialized to target virus infected cells. Rumi can also be thought of as a Memory CD8 T cell, with her mother having been the previous generation of activated CD8 T cell. During a virus infection, activated CD8 T cells divide to create a clonal army of CD8 T cells. Most of those CD8 T cells will die during the battle, but a small population remains, that retains the “memory” of the virus they are meant to target, and stay dormant in the body until that virus infection is encountered again.

Derpy becomes a Dendritic Cell ~ Dendritic cells are constantly touching and eating things in their environment, and taking what it’s eaten to present to T cells. In this way, when a Dendritic Cell has taken up a portion of a virally infected cell, T cells will be alerted of the infection by physically touching the portion of viral protein that the dendritic cell “spitst” back out to present to the T cell.

Jinu becomes the Virally Infected cell ~ in an effort to heal the body and prevent the infection from spreading, CD8 T cells must kill the virally infected cells. During this killing act, CD8 T cells and the virally infected cells can be in physical contact for hours so that the killing blows, enzymes called Perforin and Granzymes can be delivered from the CD8 T cell into the body of the virally infected cells. These enzymes create holes in the virally infected cells, leading to the death of the infected cell and the quenching of the infection.

For years, I’ve been wanting to build a pipeline that uses multimedia storytelling to place scientific communication at the intersection of education and entertainment. For K-Pop Demon Hunters ~ Immune Edition, this project is a personal one. The movie resonated deeply with the immigrant part of my upbringing - the non-ending strive to keep pushing toward a goal that seems to outweigh every other part of life. Simultaneously, the immunologist and science communicator in me kept seeing small pops of opportunities to anthropomorphize our immune cells to the memorable characters depicted in the story. Adding to that, a dose of “I just want to make fast paced video that ties pop culture in with biology!”, and I’ve signed a contract with an idea to bring it to fruition.

So here it is! As a science communicator who loves biology and a good story, being able to marry the two is a manifestation of pure joy. I hope that if you’ve enjoyed the movie, or have little ones who do, that the immunology tie-ins can also become an conversation point around the fascinating world of immune cells that are little demon hunters who live in our bodies, who fights ceaselessly for their world - our health.

Basics of the Proteasome - a comedic short

Sometimes, silly beats all else, and when science can be communicated with accuracy while being silly - you hit gold.

This short was created in collaboration with Biologyto, a vastly successful instagram channel on biology and research life. By reaching for humor in this depiction of proteasome function, this short was shared by our audience thousands of times and reached the upper tens of thousands of people within days, uniting people from around the world by being playful.

Below is the text that accompanied the post:

—-

WHEN THE RIBOSOME MAKES A MISTAKE 🧬👀

Ribosomes are usually incredible at translating mRNA into perfectly folded proteins. But every once in a while, they make a mistake, and a protein comes out completely wrong! 🥴📉

Instead of letting these defective proteins build up and cause chaos, your cells have a brilliant recycling system. Here is how it works: ➡️👀

🏷️ The Tag: The moment a misfolded protein is detected, molecules called Ubiquitin quickly latch onto it, acting as a cellular "kiss of death."

🍽️ The Feast: The Proteasome recognizes this tag, swoops in, and completely engulfs the defective protein.

♻️ The Recycle: The Proteasome chews up the misfolded protein, breaking it down into fresh peptides and amino acids that the cell can reuse to build new, healthy proteins!

Primer to Epigenetics - adding animation to hand gestures from existing interviews

Do you gesture with your hands when trying to explain molecular biology? I know I do!

People use gestures to visually represent what they picture in their mind while talking. Unfortunately, unless you’re already familiar with the subject matter and can conjure up those images as the speaker is speaking and gesturing, the gestures become ineffective - so let’s fix that!

Adding simple and effective animations to an existing interview not only save time and budget for the production pipeline, but also help both your expert in delivering the message, and your audience in receiving it.

What is required is an animator who understands the science and can empathize with both the speaker on what they want to convey, and the audience for how they want to learn.

Fluorescence Activated Cell Sorting - an animated loop for a classroom curriculum

Fluorescence Activated Cell Sorting (FACS) is a foundational technique used in immunology research to separate a mixture of cells into pure cellular populations based on properties that are unique to each cell type.

I recently created this looping animation for Dr. Richard Cross, Director of the Immunology Flow Cytometry core at St. Jude Children’s Research Hospital as a teaching tool to show students and trainees the inner workings of a FACS instrument.

What types of instrumentations and core techniques do you use in your field? How would you use animations to introduce learners to these tools and techniques to help them prepare for working in the laboratory?

Using animations to summarize a phenotype or mechanism can be a powerful way to communicate your research to your audience. Dynamic visuals that are aligned and focused to your message helps your audience see and hear your message simultaneously, enabling more rapid understanding and enhancing memorability. An aesthetic visual inspires curiosity as well, encouraging viewers to want to learn more, engage in discussions, which can further enlighten the investigators on which future avenues of research may be the most fruitful to prioritize. 

This animation depicting a ballooning mitochondrial morphology resulting from loss of mitochondrial protein MIC60 was made to accompany a flash talk for first author Stephanie Rockfield, PhD at EUROMIT 2026. The animation was created using Blender, and based upon microscopy images and videos provided by Dr. Rockfield. 

Med Journal Cover - selected for the May 2026 issue

Cover art for Meyer et al. “Rethinking the role of synergy calculations in the next century of drug combination discovery”

2026 marks 100 years since Siegfried Walter Loewe first proposed a mathematical framework for the drug synergy effect - a promising idea where the use of drug combinations may create synergistic therapeutic effects that surpass the additive efficacy of individual component drugs. However, in the century to come, the idea has proven to be more complicated to achieve in practice.

This artwork - featured on the cover of the Med journal, May 2026 issue, accompanies Meyer at el., a synthesis article that invites researchers and practitioners to re-evaluate efforts around optimizing for drug combination efficacy.

The layers of the cake represent 3 key interconnected observations described in the article, built upon clinical examples of successful (and failed) drug combinations, which are represented by the pills and chemical structures whose identity are listed on the placard at bottom right. Pills and chemical structures are also matched in each cake slice in the background. Tribute to Loewe’s seminal 1926 paper and central graph can be found at bottom left.

This short was inspired by the research article by Uenoyama et al. where the authors found that Nepetalactol (C10 H16 O2), a natural mosquito repellant in catnip and silver vine, also triggers endorphin release in cats and other felines. When cats sense this compound, the mu-opioid receptors in the olfactory centers of their brain get triggered, followed by rubbing and rolling behavior that gets more insect repellant on their face and body, especially the areas around the eyes that have less fur and can be more sensitive to mosquito bites. Researchers think that evolutionarily, this response may help wild felines protect themselves against bug bites while hunting, since felines typically stalk their pray by crouching low to the ground and hiding in tall grasses that are laced with insects.

Oxygen Binding Kinetics of Hemoglobin in 3D
Re-imagining a textbook lesson.

Do you remember learning about the oxygen binding kinetics of hemoglobin as a still graph in the classroom and textbooks? What if we can see the oxygen molecules slide into a 3D hemoglobin as it travels the curve like a monorail?

This animation, made for a high school learning module, reimagines the oxygen binding curve of hemoglobin as a dynamic process. The adult hemoglobin protein structure is imported from Protein Data Bank (PDB 2H35), with each of the 4 oxygen molecules sliding into each Heme subunit as hemoglobin travels the signature sigmoidal curve of binding kinetics.

Conceptual and symbolic 3D rendering of Erythrocyte development.

Erythrocyte maturation
An exploration into depth & perspective in conveying cellular maturation.

This 3D render shows 5 cells representing the 5 major stages of erythrocyte development, dropping onto a frosted glass slide. From top to bottom, they are hemocytoblast, proerythroblast, erythroblast, reticulocyte, and erythrocyte. Their proximity to the surface of the glass slide represent lineage commitment and a loss of self proliferative capacity, with the ejected nucleus of the reticulocyte being a pivotal determinant against proliferative capacity.

Clotting Cascade 2D animation

This 2D animation of the clotting cascade was custom built for a learning module, where independent 2D assets can be used to integrate with module software for an interactive learner experience.

Animated Preview for Biostatistics Software - lsBART

location smoothed Bayesian Additive Regression Trees

Biostatistics and data sciences critically contribute to both rigor and discovery in modern day biomedical research. Effective dissemination of biostatistical and data science tools help establish new collaborations and push the bounds of scientific and medical possibilities.

This motion-graphics based summary describes lsBART - a biostatistical software developed by St. Jude faculty Zachary Wooten, Ph.D., used for AI-assisted medical imaging analysis.

Zachary T Wooten et al. Location smoothed Bayesian additive regression trees: a method for interpretable and robust quality assurance of organ contours in radiotherapy treatment planning, Journal of the Royal Statistical Society Series C: Applied Statistics, Volume 74, Issue 5, December 2025, Pages 1301–1320, https://doi.org/10.1093/jrsssc/qlaf024

This, along with a series of 7 other biostatistical animated previews were built to enable easier understanding of recently developed biostatistical software.

“Caitlin was a huge help to me and my research group. She worked with us to create a beautifully detailed video that clearly explains some pretty complex AI modeling… that’s going to be key in helping us share this work more broadly …Her eye for design, attention to detail, and ability to bring clarity to technical content really made a difference.”

~ Zachary Wooten, PhD., Biostatistics Faculty

(St. Jude Children’s Research Hospital)

The full series of biostatistical software animation can be found on St. Jude Research Biostatistical Software page.

A note on process

For well-defined projects with immediate and specific use case, the final product can be delivered within 3 to 4 check-ins, at a rhythm of 2 - 7 days between check-ins, depending on the complexity of each visual build, revision, and the requester’s urgency.

An initial meeting following a client request generally establishes the aesthetics, scope, and timeline of the project. Once the project has started, I provide clients with progress updates every 2 - 7 business days. This frequency of check-ins ensure we remain on the same page and that client feedback is incorporated consistently as I build toward the final product.

Time to completion is project specific, and can be anywhere from 2 to 6 weeks from initial request to completion. Rush projects are possible, but may require refining the scope of the project to focus on immediate communication needs. In these cases, I work with clients to find alternative solutions to meet tight deadlines.

Let’s work together ~

To work with me, simply email Beiyun@cliubioanimation.studio with the following information: 

  1. Your name, email contact, and timezone

  2. Brief project description

  3. Relevant supporting material to help me better understand your vision - these can be project drafts, research papers, sample visuals, etc. 

I generally respond within 2 business days with follow-up questions and to set up a virtual meeting to discuss project details. 

My timezone is UTC-5.

Looking forward to connecting!